| ncRNA name | MEG3 |
| ncRNA Category | lncRNA |
| ID | 55384 |
| Ensembl | ENSG00000214548 |
| Synonyms | GTL2, LINC00023, NCRNA00023, onco-lncRNA-83 |
| Disease name | glaucoma |
| Species | Homo sapiens |
| Tissues/Cell_line | Tenon’s capsule fibroblasts; human fibroblast cell line SX1412-B |
| Methods | MTT assay, qRT-PCR, Western blot, RNA Binding Protein immunoprecipitation (RIP) |
| Expression pattern | down-regulated |
| Functional description | The functional interaction between lncRNA-MEG3 and Nrf2 constitutes the mechanism by which TGF-β2 induces Tenon's capsule fibroblasts proliferation after glaucoma filtration surgery via the direct binding of MEG3 to Nrf2. |
| PubMed ID | 28081465 |
| Year | 2017 |
| Title | Biological function and mechanism of lncRNA-MEG3 in Tenon's capsule fibroblasts proliferation: By MEG3-Nrf2 protein interaction. |
| Drug-related ncRNA | NO |
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